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20 April 2020 Overlapping volumes, acousto-optic modulated diffuse correlation spectroscopy for increased depth sensitivity (Conference Presentation)
Mitchell B. Robinson, Stefan A. Carp, Sava Sakadzic, Adriano Peruch, Davide Tamborini, Maria Angela Franceschini
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Proceedings Volume 11240, Photons Plus Ultrasound: Imaging and Sensing 2020; 112402T (2020) https://doi.org/10.1117/12.2546630
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Diffuse correlation spectroscopy (DCS) is an established diffuse optical technique that uses the analysis of temporal speckle intensity fluctuations to measure blood flow in tissue. As a non-invasive technique, DCS has been used to monitor patient cerebral blood flow at the bedside. Though an effective measurement tool, extra-cerebral contamination of the DCS signal limits the sensitivity to changes in brain blood flow. In order to overcome this depth sensitivity challenge, we present a method, overlapping volumes, acousto-optic modulated DCS (AOM-DCS), to improve sensitivity to deeper tissue structures.
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Mitchell B. Robinson, Stefan A. Carp, Sava Sakadzic, Adriano Peruch, Davide Tamborini, and Maria Angela Franceschini "Overlapping volumes, acousto-optic modulated diffuse correlation spectroscopy for increased depth sensitivity (Conference Presentation)", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112402T (20 April 2020); https://doi.org/10.1117/12.2546630
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KEYWORDS
Modulation
Spectroscopy
Acousto-optics
Ultrasonography
Blood circulation
Brain
Tissue optics
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