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6 March 2020 Multifunctional bimodal optoacoustic & fluorescent probes (Conference Presentation)
Dmitry A. Gorin
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Proceedings Volume 11241, Biophotonics and Immune Responses XV; 112410G (2020) https://doi.org/10.1117/12.2550529
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Modern medicine requires to combine the imaging and therapy tools in one object. Two types of nanostructured shells were elaborated. The first type of shell that exhibited the highest photoacoustic and fluorescent signals have utilized a combination of gold nanorods and indocyanine green dispersed in the matrix of biodegradable polymers. The second type based on composite indocyanine green/polymer using a self-quenching effect has been successfully prepared and characterized by fluorescent and optoacoustic tomographies. Optimal compositions and structures of nanostructured shells from point of view of photoacoustic and fluorescent signal intensities required for detection of nanostructured shell in vivo were found.
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Dmitry A. Gorin "Multifunctional bimodal optoacoustic & fluorescent probes (Conference Presentation)", Proc. SPIE 11241, Biophotonics and Immune Responses XV, 112410G (6 March 2020); https://doi.org/10.1117/12.2550529
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KEYWORDS
Nanostructuring
Photoacoustic spectroscopy
Biomedical optics
In vivo imaging
Nanoparticles
Visualization
Cancer
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