Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography

Arata Miyazawa; Shuichi Makita; En Li; Kohei Yamazaki; Masaki Kobayashi; Shingo Sakai; Yoshiaki Yasuno

doi:10.1117/12.2544687

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13 February 2020 Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography

Arata Miyazawa, Shuichi Makita, En Li, Kohei Yamazaki, Masaki Kobayashi, Shingo Sakai, Yoshiaki Yasuno

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Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 1124214 (2020) https://doi.org/10.1117/12.2544687
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Polarization-sensitive optical coherence elastography was developed. It integrates Jones matrix-based polarization-sensitive optical coherence tomography with compression OCE. The method simultaneously measures OCT, attenuation coefficient, birefringence, and tissue mechanical properties. Ex-vivo porcine esophagus was measured by PS-OCE. Evident alteration caused by heat-induced denaturation was obtained in almost all of the optical and mechanical properties including attenuation coefficient, birefringence, in-plane lateral displacement, and microstructural deformation.

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Arata Miyazawa, Shuichi Makita, En Li, Kohei Yamazaki, Masaki Kobayashi, Shingo Sakai, and Yoshiaki Yasuno "Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124214 (13 February 2020); https://doi.org/10.1117/12.2544687

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