Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization

Shun Takeda; Hiroshi Kumagai; Mineyuki Hattori

doi:10.1117/12.2544572

17 February 2020 Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization

Shun Takeda, Hiroshi Kumagai, Mineyuki Hattori

Proceedings Volume 11243, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII; 112431W (2020) https://doi.org/10.1117/12.2544572
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

In recent years, MRI using a rare gas has attracted attention. Rare gas MRI can perform imaging of lungs with few protons and can also evaluate gas dynamics and hemodynamics. Attempts have been made to enhance the signal intensity by hyperpolarizing nuclear spins to obtain NMR signals from the gas. This hyperpolarization technology is also expected to be effective when combined with low-field MRI including permanent magnet type. In this study, a xenon (¹²⁹Xe) hyperpolarization system using a 795nm laser was constructed and evaluated using a 0.3T NMR system. As a result, it was shown that the NMR signal intensity from ¹²⁹Xe can be enhanced 1.5 times with a polarization of 30 minutes.

Citation Download Citation

Shun Takeda, Hiroshi Kumagai, and Mineyuki Hattori "Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization", Proc. SPIE 11243, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII, 112431W (17 February 2020); https://doi.org/10.1117/12.2544572

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KEYWORDS

Xenon

Polarization

Magnetic resonance imaging

Rubidium

Optical pumping

Noble gases

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