Functional imaging of the retina with phase-sensitive full-field swept-source optical coherence tomography (Conference Presentation)

Dierck Hillmann; Clara Pfäffle; Hendrik Spahr; Felix Hilge; Sazan Burhan; Katharina Gercke; Yoko Miura; Gereon M. Hüttmann

doi:10.1117/12.2545969

11 March 2020 Functional imaging of the retina with phase-sensitive full-field swept-source optical coherence tomography (Conference Presentation)

Dierck Hillmann, Clara Pfäffle, Hendrik Spahr, Felix Hilge, Sazan Burhan, Katharina Gercke, Yoko Miura, Gereon M. Hüttmann

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Proceedings Volume 11249, Quantitative Phase Imaging VI; 112490U (2020) https://doi.org/10.1117/12.2545969
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We demonstrate functional in vivo imaging of photoreceptor and neuronal layers within the living human retina by looking at the expansion of their optical path length. To this end, we use a special full-field swept-source optical coherence tomography system that acquires all lateral points in parallel, achieving a high-speed data acquisition with up to 200 volumes per second. A combination of computational motion and aberration correction with a suitable phase evaluation scheme yields minuscule changes after exposing the photoreceptors to a white light stimulus.

Conference Presentation

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Dierck Hillmann, Clara Pfäffle, Hendrik Spahr, Felix Hilge, Sazan Burhan, Katharina Gercke, Yoko Miura, and Gereon M. Hüttmann "Functional imaging of the retina with phase-sensitive full-field swept-source optical coherence tomography (Conference Presentation)", Proc. SPIE 11249, Quantitative Phase Imaging VI, 112490U (11 March 2020); https://doi.org/10.1117/12.2545969

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KEYWORDS

Optical coherence tomography

Retina

Functional imaging

Tissue optics

Tissues

Adaptive optics

Cameras

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