Visualization of membrane potential changes induced by oscillating electric fields (Conference Presentation)

Allen Kiester; Zach Coker; Bennett Ibey; Joel Bixler

doi:10.1117/12.2546029

10 March 2020 Visualization of membrane potential changes induced by oscillating electric fields (Conference Presentation)

Allen Kiester, Zach Coker, Bennett Ibey, Joel Bixler

Author Affiliations +

Proceedings Volume 11250, High-Speed Biomedical Imaging and Spectroscopy V; 112500O (2020) https://doi.org/10.1117/12.2546029
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Recently, Beier et al. a new imaging system called a streak camera microscope (SCM) that is able to resolve sub nanosecond membrane potential changes in cells loaded with FluoVolt dye. This technique opens the window into the response of cell membrane potential to rapidly applied electric fields. Having demonstrated this response on single bipolar and unipolar electric pulses, we have begun to investigate the rapid charging and discharging of the plasma membrane during bursts of AC frequencies. We believe that understanding the dynamics of plasma membrane charging during AC pulses will better inform those using such pulses to modify cell behavior.

Conference Presentation

Citation Download Citation

Allen Kiester, Zach Coker, Bennett Ibey, and Joel Bixler "Visualization of membrane potential changes induced by oscillating electric fields (Conference Presentation)", Proc. SPIE 11250, High-Speed Biomedical Imaging and Spectroscopy V, 112500O (10 March 2020); https://doi.org/10.1117/12.2546029

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