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10 March 2020 Rapid switching between various wavelength regions for coherent Raman imaging with a robust all-fiber source (Conference Presentation)
Tim Hellwig, Maximilian Brinkmann, Carsten Fallnich
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Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 1125118 (2020) https://doi.org/10.1117/12.2545491
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
We present coherent anti-Stokes Raman (CARS) imaging with our robust all-fiber optical parametric oscillator (FOPO) that is tunable across the whole bio-relevant spectral region (700 to 3530 wavenumbers) in less than 5 ms. The all-fiber operation allows to operate the FOPO on a regular laboratory cart, maximize temporal pulse overlap by dispersion management and inherently minimize beam-pointing. We present first CARS images of DMSO-d6 infiltration into mouse skin imaged in the silent as well as CH-stretch region without any alignment other than electronically tuning the wavelength. The FOPO is ideally suited for label-free, hyperspectral imaging, e.g., in translational research.
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Tim Hellwig, Maximilian Brinkmann, and Carsten Fallnich "Rapid switching between various wavelength regions for coherent Raman imaging with a robust all-fiber source (Conference Presentation)", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125118 (10 March 2020); https://doi.org/10.1117/12.2545491
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KEYWORDS
Coherence imaging
Raman spectroscopy
Switching
Laser systems engineering
Fiber lasers
Imaging systems
Optical fibers
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