High-resolution multimodal flexible coherent Raman endoscope (Conference Presentation)

Hervé Rigneault; Viktor Tsvirkun; Vasyl Mytskaniuk; Marc Fabert; Frédéric Louradour; Alexandre Kudlinski

doi:10.1117/12.2545038

10 March 2020 High-resolution multimodal flexible coherent Raman endoscope (Conference Presentation)

Hervé Rigneault, Viktor Tsvirkun, Vasyl Mytskaniuk, Marc Fabert, Frédéric Louradour, Alexandre Kudlinski

Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 112511C (2020) https://doi.org/10.1117/12.2545038
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We present a flexible, compact, and multimodal nonlinear endoscope (2.2 mm outer diameter) based on a resonantly scanned negative curvature hollow-core double-clad fiber. The fiber design allows distortion-less, background-free delivery of femtosecond and picosecond excitation pulses and the back-collection of nonlinear signals through the same fiber. Sub-micron spatial resolution together with large field of view is made possible by the combination of a miniature objective lens together with a silica microsphere lens inserted into the fiber core. We demonstrate coherent anti-Stokes Raman scattering, 2-photon fluorescence and second harmonic generation imaging at a rate of 10 frames/s.

Conference Presentation

Citation Download Citation

Hervé Rigneault, Viktor Tsvirkun, Vasyl Mytskaniuk, Marc Fabert, Frédéric Louradour, and Alexandre Kudlinski "High-resolution multimodal flexible coherent Raman endoscope (Conference Presentation)", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 112511C (10 March 2020); https://doi.org/10.1117/12.2545038

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