Progress in angle-resolved low-coherence interferometry for real-time detection of epithelial dysplasia (Conference Presentation)

Zachary A. Steelman; Derek Ho; Yang Zhao; Haoran Zhang; Evan Jelly; Ge Song; Wesley Y. Kendall; Michael Crose; Brian Cox; Kengyeh K. Chu; Adam P. Wax

doi:10.1117/12.2545173

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10 March 2020 Progress in angle-resolved low-coherence interferometry for real-time detection of epithelial dysplasia (Conference Presentation)

Zachary A. Steelman, Derek Ho, Yang Zhao, Haoran Zhang, Evan Jelly, Ge Song, Wesley Y. Kendall, Michael Crose, Brian Cox, Kengyeh K. Chu, Adam P. Wax

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Proceedings Volume 11253, Biomedical Applications of Light Scattering X; 1125302 (2020) https://doi.org/10.1117/12.2545173
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Angle-resolved low-coherence interferometry (a/LCI) is an optical technique which uses inverse models of light scattering to predict the size and density of cell nuclei, a significant biomarker of precancer. In recent years, substantial progress has occurred in a/LCI technology, particularly in novel instrumentation for the detection of dysplasia in the cervix and the esophagus. This abstract summarizes recent developments in a/LCI, with a focus on developments over the previous four years. Clinical studies in the cervix, novel optical instrumentation addressing the cervix and esophagus, and novel applications related to Alzheimer’s disease are discussed.

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Zachary A. Steelman, Derek Ho, Yang Zhao, Haoran Zhang, Evan Jelly, Ge Song, Wesley Y. Kendall, Michael Crose, Brian Cox, Kengyeh K. Chu, and Adam P. Wax "Progress in angle-resolved low-coherence interferometry for real-time detection of epithelial dysplasia (Conference Presentation)", Proc. SPIE 11253, Biomedical Applications of Light Scattering X, 1125302 (10 March 2020); https://doi.org/10.1117/12.2545173

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