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11 March 2020 Energetic ultrafast source tunable between 940 to 1250 nm for multi-photon microscopy (Conference Presentation)
Yang Yu, Shaobo Fang, Hao Teng, Jiangfeng Zhu, Jun-Li Wang, Guoqing Chang, Zhiyi Wei
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Proceedings Volume 11260, Fiber Lasers XVII: Technology and Systems; 112600M (2020) https://doi.org/10.1117/12.2547023
Event: SPIE LASE, 2020, San Francisco, California, United States
Abstract
Multi-photon microscopy (MPM) has become an indispensable tool for observing biological structures and functions in vivo, benefitting from its deep penetration depth and high spatial resolution. Femtosecond pulses featuring a broad wavelength tuning range are highly desired by MPM. We demonstrate a 1-MHz ultrafast fiber-optic source that produces ~100-fs pulses tunable from 940 nm to 1250 nm with 100-nJ level pulse energy. For example, we achieved 120-fs pulses with 105-nJ energy centered at 1150 nm. This broadly tunable, energetic fs source constitutes an ideal source for deep-tissue multi-photon imaging.
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Yang Yu, Shaobo Fang, Hao Teng, Jiangfeng Zhu, Jun-Li Wang, Guoqing Chang, and Zhiyi Wei "Energetic ultrafast source tunable between 940 to 1250 nm for multi-photon microscopy (Conference Presentation)", Proc. SPIE 11260, Fiber Lasers XVII: Technology and Systems, 112600M (11 March 2020); https://doi.org/10.1117/12.2547023
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KEYWORDS
Microscopy
Multiphoton microscopy
Ultrafast imaging
Femtosecond phenomena
Imaging systems
Laser systems engineering
Ultrafast phenomena
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