Fast and high-sensitivity chemical imaging via compressive Raman microspectroscopy (Conference Presentation)

Hilton Barbosa de Aguiar

doi:10.1117/12.2546262

9 March 2020 Fast and high-sensitivity chemical imaging via compressive Raman microspectroscopy (Conference Presentation)

Hilton Barbosa de Aguiar

Author Affiliations +

Proceedings Volume 11284, Smart Photonic and Optoelectronic Integrated Circuits XXII; 112841S (2020) https://doi.org/10.1117/12.2546262
Event: SPIE OPTO, 2020, San Francisco, California, United States

Abstract

Raman imaging is recognized as a powerful label-free approach to provide contrasts based on chemical selectivity. Nevertheless, Raman-based microspectroscopy has drawbacks mostly due to its inherent overwhelming data size, which slows imaging speeds, and non-trivial post-processing, in particular for non-specialists in vibrational spectroscopy. In parallel, compressive sensing has shown a paradigm shift approach where one can computationally reconstruct accurate information from highly undersampled data. Following the compressive sensing spirit, compressive Raman microspectroscopy has emerged as a potential approach to speed up the imaging and concomitantly simplify the post-processing analysis. In this contribution, I will discuss the concepts and assumptions in compressive Raman, in particular focusing on current challenges for fast and high-sensitivity imaging of challenging biological specimens.

Conference Presentation

Citation Download Citation

Hilton Barbosa de Aguiar "Fast and high-sensitivity chemical imaging via compressive Raman microspectroscopy (Conference Presentation)", Proc. SPIE 11284, Smart Photonic and Optoelectronic Integrated Circuits XXII, 112841S (9 March 2020); https://doi.org/10.1117/12.2546262

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