Finding novelty with uncertainty

Jacob C. Reinhold; Yufan He; Shizhong Han; Yunqiang Chen; Dashan Gao; Junghoon Lee; Jerry L. Prince; Aaron Carass

doi:10.1117/12.2549341

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10 March 2020 Finding novelty with uncertainty

Jacob C. Reinhold, Yufan He, Shizhong Han, Yunqiang Chen, Dashan Gao, Junghoon Lee, Jerry L. Prince, Aaron Carass

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Proceedings Volume 11313, Medical Imaging 2020: Image Processing; 113130H (2020) https://doi.org/10.1117/12.2549341
Event: SPIE Medical Imaging, 2020, Houston, Texas, United States

Abstract

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely. To address this challenge, we propose a Bayesian deep learning method that learns to translate healthy computed tomography images to magnetic resonance images and simultaneously calculates voxel-wise uncertainty. Since high uncertainty occurs in pathological regions of the image, this uncertainty can be used for unsupervised anomaly segmentation. We show encouraging experimental results on an unsupervised anomaly segmentation task by combining two types of uncertainty into a novel quantity we call scibilic uncertainty.

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Jacob C. Reinhold, Yufan He, Shizhong Han, Yunqiang Chen, Dashan Gao, Junghoon Lee, Jerry L. Prince, and Aaron Carass "Finding novelty with uncertainty", Proc. SPIE 11313, Medical Imaging 2020: Image Processing, 113130H (10 March 2020); https://doi.org/10.1117/12.2549341

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