In order to research the imaging effect of the IRFPA ROIC, the imaging simulation system is developed which is the PC-DAQ system based on virtual instrument technology. The system uses powerful software and hardware resources of computer and high performance DAQ data acquisition card to complete the acquisition and display of IRFPA ROIC image signal. The hardware of the system is composed of signal source, junction box, drive circuit board, PCI MIO16E-1 data acquisition card and PC. According to the driving timing requirement of IRFPA imaging, the field synchronization signal is used to control the triggering start of the acquisition card, and the scanning clock signal is used as A/D clock to control the accurate sampling of each pixel. Video output signal, field synchronization signal, pre-trigger signal of data acquisition card and A/D clock signal are connected with data acquisition card through junction box. The time sequence control of the acquisition card is realized by software programming to complete the acquisition of one-dimensional ROIC signal. In the software platform, the signal is converted to display image in two-dimensional space. At the same time, ROIC image signal is processed by software system, such as background noise correction, invalid pixel compensation, gray histogram enhancement, pseudo-color coding and so on, so that users can choose image display mode. By the experiment of 128*128 HgCdTe IRFPA ROIC, it is valid that the system can visually simulate the imaging effect of ROIC image, and provide a good algorithm basis for the construction of IRFPA imaging system, and provide a reference for device quality evaluation.