Low-cost measurement of the dermal beta-carotene in the context of optical clearing

M. A. Ansari; A. Morovati; V. V. Tuchin

doi:10.1117/12.2563961

9 April 2020 Low-cost measurement of the dermal beta-carotene in the context of optical clearing

M. A. Ansari, A. Morovati, V. V. Tuchin

Proceedings Volume 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine; 1145704 (2020) https://doi.org/10.1117/12.2563961
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation

Abstract

Determining cutaneous carotenoid plays an important role in the human health and nutrition studies. Recently, compression optical clearing (OC) was applied to detect dermal carotenoid using reflection spectroscopy. This study aims to improve compression OC to detect the absorption spectrum of beta-carotene inside the human dermal skin. We utilize a combination of experimental (including compression-immersion OC) and computational OC to enhance the ability of reflectance spectroscopy to detect the beta-carotene inside palm of hand. The presented OC techniques can be applied for determining chromophores, such as melanin and bilirubin that have good abilities for nutrition and oncology researches.

Citation Download Citation

M. A. Ansari, A. Morovati, and V. V. Tuchin "Low-cost measurement of the dermal beta-carotene in the context of optical clearing", Proc. SPIE 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine, 1145704 (9 April 2020); https://doi.org/10.1117/12.2563961

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