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9 April 2020 Detection of antigen-antibody interactions in microstructured optical fibers
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Proceedings Volume 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine; 114571J (2020) https://doi.org/10.1117/12.2564400
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation
Abstract
Optical sensing is a powerful tool for recognition interactions in biosystems. Nowadays sensor systems allow to determinate the biomolecules interactions in biological fluids with high sensitivity, reproducibility and minimum standard error. Usually analyses are carried out in a heterogeneous format, which significantly complicates the procedure and increases the single analysis cost. The swap from heterogeneous to homogeneous analysis format is a promising solution. Microstructured optical fibers (MOFs) are a possible platform for creation of such sensors. Manuscript describe the possibility to detect antigen-antibody interactions in the hollow core microstructured optical fibers (HC MOFs). The determination of such interactions was carried out both in heterogeneous and homogeneous formats. Results demonstrate the prospects of HC MOF as a platform for the detection of antigen-antibody interactions.
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Pavel S. Pidenko, Andrey A. Shuvalov, Anastasia A. Zanishevskaya, and Natalia A. Burmistrova "Detection of antigen-antibody interactions in microstructured optical fibers", Proc. SPIE 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine, 114571J (9 April 2020); https://doi.org/10.1117/12.2564400
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