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9 April 2020 High-precision evaluation of stress-related properties of blood vessel walls using intravascular optical coherence elastography with forward-view probe
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Proceedings Volume 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine; 114571P (2020) https://doi.org/10.1117/12.2563849
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation
Abstract
A method for evaluation of the shear modulus for the large blood vessel walls is described. Structural images of the investigated part of the blood vessel wall with aneurysm are sequentially obtained using intravascular optical coherence tomography (IOCT) system for at least several cardiocycles. B-scans correspondent to diastole and shear deformation stages between systole and diastole are taken for the evaluation from a sequence of structural images. The pulse wave is considered to be the only deforming stimulus. The surface area of the deforming force is considered to be equal to the scanning area of the IOCT system. B-scans’ profiles are processed and plotted according to the average truncated level of the interference signal intensity. These profiles are divided into overlapping blocks. Shear deformation is estimated for overlapping blocks by the abscissa projection of the average displacement vector. The dimensions of the deformed region are to be equal to corresponding coherence probing depth. Shear modulus in the point of interest of the blood vessel wall is calculated using the classical formula and verified using known values of the Young's modulus and Poisson's ratio.
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. Yu. Potlov, S. V. Frolov, T. A. Frolova, and S. G. Proskurin "High-precision evaluation of stress-related properties of blood vessel walls using intravascular optical coherence elastography with forward-view probe", Proc. SPIE 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine, 114571P (9 April 2020); https://doi.org/10.1117/12.2563849
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