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9 April 2020 Statistical properties of GB-speckles coding the nucleotide sequences of the neuraminidase gene of Highly Pathogenic Avian Influenza A Virus (HPAIV) strains
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Proceedings Volume 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine; 114571W (2020) https://doi.org/10.1117/12.2563641
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation
Abstract
Gene-based speckles (GB-speckles) have been implied for interpretation of nucleotide sequences of the target genes of HPAIV. The 1st order statistics and correlation functions of 2D speckle structures corresponding to the several nucleotide sequences of HPAIV have been analyzed. The GB-speckles, generated for highly-pathogenic strains A/Gs/HK/739.2/02 (H5N1) and HPAIV (A/Chicken/Hong Kong/YU562/01 (H5N1)) neuraminidase (NA) have been compared with the speckles, related to three low-pathogenic strains (Influenza A virus (A/chicken/Ganzhou/GZ43/2016(H3N2)) segment 6 neuraminidase (NA) gene, Influenza A virus A/pheasant/Korea/LBM180/2008(H9N2)) segment 6 neuraminidase (NA) gene, and Influenza A virus A/chicken/Alkharj/910/2018(H5N8)) segment 6 neuraminidase (NA) gene). Perspectives of fast and precise discrimination of nucleotide sequences of the different avian influenza strains, including HPAIV variants, based on GBspeckles, are demonstrated.
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Onega Ulianova, Nadejda Filonova, Sergey Zaytsev, Alexander Ulyanov, Yury Saltykov, Sergey Ulyanov, and Valentina Feodorova "Statistical properties of GB-speckles coding the nucleotide sequences of the neuraminidase gene of Highly Pathogenic Avian Influenza A Virus (HPAIV) strains", Proc. SPIE 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine, 114571W (9 April 2020); https://doi.org/10.1117/12.2563641
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