Transcutaneous monitoring of hemoglobin derivatives during methemoglobinemia using spectral diffuse reflectance imaging

Fahima Khatun; Izumi Nishidate

doi:10.1117/12.2573224

15 June 2020 Transcutaneous monitoring of hemoglobin derivatives during methemoglobinemia using spectral diffuse reflectance imaging

Fahima Khatun, Izumi Nishidate

Author Affiliations +

Proceedings Volume 11521, Biomedical Imaging and Sensing Conference 2020; 115210G (2020) https://doi.org/10.1117/12.2573224
Event: SPIE Technologies and Applications of Structured Light, 2020, Yokohama, Japan

Abstract

We propose a non-invasive and non-contact imaging technique based on the diffuse reflectance spectroscopy to evaluate the concentrations of methemoglobin (metHb), oxygenated hemoglobin (HbO), and deoxygenated hemoglobin (HbR) simultaneously. Experiments with in vivo rat exposed to sodium nitrite (NaNO2) shows the feasibility of the method for monitoring changes in metHb, HbO, and HbR concentrations during methemoglobinemia.

Citation Download Citation

Fahima Khatun and Izumi Nishidate "Transcutaneous monitoring of hemoglobin derivatives during methemoglobinemia using spectral diffuse reflectance imaging", Proc. SPIE 11521, Biomedical Imaging and Sensing Conference 2020, 115210G (15 June 2020); https://doi.org/10.1117/12.2573224

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