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10 October 2020 Broadband photoacoustic microscopy based on surface plasmon sensing
Wei Song
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Proceedings Volume 11549, Advanced Optical Imaging Technologies III; 115490S (2020) https://doi.org/10.1117/12.2573462
Event: SPIE/COS Photonics Asia, 2020, Online Only
Abstract
The ability to accurately respond pressure transients is critical for biomedical photoacoustic (PA) imaging. The routinely-adopted piezoelectric transducer usually operates at limited sensitivity and bandwidth, resulting in inadequate response to PA impulses. Here, we propose surface plasmon sensing for PA wave detection. Relying on modulations to surface plasmon polaritons from temporal ultrasonic perturbations, PA pressure transients are retrieved by recording variations in the reflected light. We relalize PA detection with a broad bandwidth of approximately 190 MHz and a sensitivity of ~100 Pa. In vivo volumetric imaging is obtained label-freely by PA microscopy incorporating a surface plasmon sensor.
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Wei Song "Broadband photoacoustic microscopy based on surface plasmon sensing", Proc. SPIE 11549, Advanced Optical Imaging Technologies III, 115490S (10 October 2020); https://doi.org/10.1117/12.2573462
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KEYWORDS
Surface plasmons
Biomedical optics
Photoacoustic microscopy
Sensors
Tissue optics
Absorption
Acoustics
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