Heptamethine cyanine-based small molecular cancer theranostic agents

Xie Huang; Shenglin Luo

doi:10.1117/12.2573854

10 October 2020 Heptamethine cyanine-based small molecular cancer theranostic agents

Xie Huang, Shenglin Luo

Proceedings Volume 11553, Optics in Health Care and Biomedical Optics X; 115530T (2020) https://doi.org/10.1117/12.2573854
Event: SPIE/COS Photonics Asia, 2020, Online Only

Abstract

Cancer theranostic agents with a combination of cancer therapy and real-time imaging/diagnosis, provide a promising prospect for individualized and precise cancer treatment. Here, a series of structure-inherent multifunctional fluorescent small molecules, namely heptamethine cyanine dyes, were developed simultaneously for tumor-targeting, near-infrared imaging and therapy. Obtainment of cancer theranostic agents based on structure-inherent multifunctional small molecules, is a simple and straightforward way, and small molecules have advantages of easy, low-cost and large-scale synthesis, including good repeatability and quality control. Therefore, our findings may provide an alternative approach to develop multifunctional cancer theranostic agents.

Conference Presentation

Citation Download Citation

Xie Huang and Shenglin Luo "Heptamethine cyanine-based small molecular cancer theranostic agents", Proc. SPIE 11553, Optics in Health Care and Biomedical Optics X, 115530T (10 October 2020); https://doi.org/10.1117/12.2573854

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