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5 March 2021 In vivo endoscopic multifunctional optical coherence tomography imaging of lungs periphery before and after bronchial thermoplasty
Margherita Vaselli, Pieta Wijsman, Joy Willemse, Annika W. M. Goorsenberg, Fabio Feroldi, Jouke T. Annema, Peter I. Bonta, Johannes F. de Boer
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Proceedings Volume 11620, Endoscopic Microscopy XVI; 1162009 (2021) https://doi.org/10.1117/12.2578351
Event: SPIE BiOS, 2021, Online Only
Abstract
We present a motorized distal scanning endoscope with an outer diameter of 1.35 mm and 52 fps rotation speed for in vivo imaging in the peripheral airways of lungs [1]. Lung segments of an asthma patient pre and post bronchial thermoplasty (BT) treatment were imaged [2]. Optical coherence tomography (OCT) intensity images, attenuation coefficient (AC) images and polarization sensitive OCT (PS-OCT) images showing both birefringence, optic axis uniformity (OAxU) and optic axis (OA) orientation were extracted from the acquired data. PS-OCT endoscopy visualized airway smooth muscle layer thickness and location pre and post BT treatment as means to predict its effectiveness.
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Margherita Vaselli, Pieta Wijsman, Joy Willemse, Annika W. M. Goorsenberg, Fabio Feroldi, Jouke T. Annema, Peter I. Bonta, and Johannes F. de Boer "In vivo endoscopic multifunctional optical coherence tomography imaging of lungs periphery before and after bronchial thermoplasty", Proc. SPIE 11620, Endoscopic Microscopy XVI, 1162009 (5 March 2021); https://doi.org/10.1117/12.2578351
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KEYWORDS
Optical coherence tomography
Coherence imaging
In vivo imaging
Lung
Endoscopy
Optical imaging
Birefringence
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