Mapping attenuation coefficient characteristics of cataracts with optical coherence tomography

Pablo Eugui; Danielle J. Harper; Johanna Gesperger; Antonia Lichtenegger; Conrad W. Merkle; Martin Glösmann; Bernhard Baumann

doi:10.1117/12.2578268

5 March 2021 Mapping attenuation coefficient characteristics of cataracts with optical coherence tomography

Pablo Eugui, Danielle J. Harper, Johanna Gesperger, Antonia Lichtenegger, Conrad W. Merkle, Martin Glösmann, Bernhard Baumann

Author Affiliations +

Proceedings Volume 11623, Ophthalmic Technologies XXXI; 116230V (2021) https://doi.org/10.1117/12.2578268
Event: SPIE BiOS, 2021, Online Only

Abstract

Optical coherence tomography (OCT) is an interferometric imaging technique that provides non-destructive volumetric visualization of tissues. OCT has been previously proposed as a method to analyze lens cataracts in humans and animal models. In our previous work we showcased the use of a custom-made OCT system to image the crystalline lenses of mice in vivo based on scattering contrast. We now extend our previous results and propose the attenuation coefficient as a parameter for quantitative mapping the lenticular opacities, revealing a significant difference between eyes with ocular cataracts and normal eyes.

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Citation Download Citation

Pablo Eugui, Danielle J. Harper, Johanna Gesperger, Antonia Lichtenegger, Conrad W. Merkle, Martin Glösmann, and Bernhard Baumann "Mapping attenuation coefficient characteristics of cataracts with optical coherence tomography", Proc. SPIE 11623, Ophthalmic Technologies XXXI, 116230V (5 March 2021); https://doi.org/10.1117/12.2578268

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