Optical properties of porcine oral mucosa at application of iodine preparation based on glycerol

A. A. Selifonov; V. V. Tuchin

doi:10.1117/12.2578793

15 March 2021 Optical properties of porcine oral mucosa at application of iodine preparation based on glycerol

A. A. Selifonov, V. V. Tuchin

Proceedings Volume 11626, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021; 116260X (2021) https://doi.org/10.1117/12.2578793
Event: SPIE BiOS, 2021, Online Only

Conference Poster

Abstract

The use of diffuse reflection spectroscopy made it possible to determine the optical properties of the mucous membrane of the oral cavity of a pig. The binary diffusion coefficient of iodine in Lugol's composition (aqueous solution of iodine (0.01 w/w), potassium iodide (0.02 w/w) and glycerol (0.94 w/w)) was determined for the first time ex vivo in the lining of the alveolar gingiva pigs: (8.86±0.75)·10^–7 cm²/s. For the first time, the binary diffusion coefficient of glycerol was determined in the composition of Lugol (an aqueous solution of iodine (0.01 w/w), potassium iodide (0.02 w/w), and glycerol (0.94 w/w)) ex vivo in the lining of the alveolar gingiva pigs: (6.44±0.62)·10^-7cm²/s. It was revealed that after complete staining of the gingiva with a dye, radiation does not pass into the biological tissue from 200-600 nm, which includes the areas of iodine absorption peaks, and starting from 650-800 nm, the effect of optical clearing is observed with an efficiency of up to 120%.

Citation Download Citation

A. A. Selifonov and V. V. Tuchin "Optical properties of porcine oral mucosa at application of iodine preparation based on glycerol", Proc. SPIE 11626, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021, 116260X (15 March 2021); https://doi.org/10.1117/12.2578793

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