Presentation
5 March 2021 Large scale mapping of the cortical microvascular velocities by the dynamic light scattering optical coherence tomography
Author Affiliations +
Abstract
We present a framework to coregister a large set of blood flow measurements from the cortical microvascular segments obtained by DLS-OCT with the microvascular angiogram obtained using TPM. By using this framework, we estimated the distributions of the mean RBC velocities in arterioles, venules, and capillaries, and as a function of the branching order from over 1,000 microvascular segments. The developed tools will help with more quantitative analysis of the large data sets obtained by OCT and TPM in the studies involving normal brain functioning, progression of various diseases, and numerical modeling of the oxygen transport in the microvascular networks.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Mohammed Alfadhel, Qi Pian, Jianbo Tang, Grace Lee, Baoqiang Li, Buyin Fu, Yagmur Ayata, David Boas, Timothy Secomb, and Sava Sakadžic "Large scale mapping of the cortical microvascular velocities by the dynamic light scattering optical coherence tomography", Proc. SPIE 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 116290Z (5 March 2021); https://doi.org/10.1117/12.2583146
Advertisement
Advertisement
KEYWORDS
Optical coherence tomography

Dynamic light scattering

Blood circulation

Angiography

Oxygen

Diffusion

Image segmentation

Back to Top