Multimodal intrinsic contrast imaging for nerve discrimination in vivo

Graham A. Throckmorton; Justin S. Baba; Anita Mahadevan-Jansen

doi:10.1117/12.2576531

5 March 2021 Multimodal intrinsic contrast imaging for nerve discrimination in vivo

Graham A. Throckmorton, Justin S. Baba, Anita Mahadevan-Jansen

Proceedings Volume 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX; 116310B (2021) https://doi.org/10.1117/12.2576531
Event: SPIE BiOS, 2021, Online Only

Abstract

Inadvertent nerve injury is a common complication during many surgical procedures. Intraoperative localization of nerves could reduce the risk of nerve injury and improve patients’ quality of life post-operation. To address this need, we combine diffuse reflectance and polarization imaging techniques into a single imaging system for in vivo nerve mapping. Both modalities successfully localize nerves within the field of view in an in vivo rat model and together provide enhanced contrast in relation to the surrounding tissues. The results of this study provide valuable insight into the future development of a real-time imaging system for clinical translation.

Conference Presentation

Citation Download Citation

Graham A. Throckmorton, Justin S. Baba, and Anita Mahadevan-Jansen "Multimodal intrinsic contrast imaging for nerve discrimination in vivo", Proc. SPIE 11631, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIX, 116310B (5 March 2021); https://doi.org/10.1117/12.2576531

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