Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

Berkan Lafci; Elena Merčep; Joaquin L. Herraiz; Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1117/12.2577907

5 March 2021 Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

Berkan Lafci, Elena Merčep, Joaquin L. Herraiz, Xosé Luís Deán-Ben, Daniel Razansky

Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 116422L (2021) https://doi.org/10.1117/12.2577907
Event: SPIE BiOS, 2021, Online Only

Abstract

Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.

Conference Presentation

Citation Download Citation

Berkan Lafci, Elena Merčep, Joaquin L. Herraiz, Xosé Luís Deán-Ben, and Daniel Razansky "Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116422L (5 March 2021); https://doi.org/10.1117/12.2577907

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available