Facile synthesis of fluorescent carbon quantum dots and their potential application in cancer theranostics

Bryan Christian A. Karingal; Yih-Chih Hsu

doi:10.1117/12.2584578

5 March 2021 Facile synthesis of fluorescent carbon quantum dots and their potential application in cancer theranostics

Bryan Christian A. Karingal, Yih-Chih Hsu

Proceedings Volume 11643, Biophotonics and Immune Responses XVI; 1164309 (2021) https://doi.org/10.1117/12.2584578
Event: SPIE BiOS, 2021, Online Only

Abstract

Carbon quantum dots (CQDs) are an emerging research area in the biomedical field due to their biocompatibility and multifunctionality. Herein, we report CQDs synthesized in a green, fast, facile manner in a recyclable mineral oilmediated pyrolysis medium using citric acid as the main carbon source and thiourea as N- and S-doping source. The assynthesized CQDs exhibit excitation-dependent photoemission (Φ = 0.57) with notable energy upconversion behavior at longer wavelengths, suggesting possible utilization in multiphoton microscopy. FT-IR characterization suggest diverse functional groups on the surface which include carboxylic acids, amines, and thiocyanates among others. Photothermal analysis supported the NIR-emissive behavior and showed that CQD solution temperature could potentially increase nearly 20°C higher after 10 min irradiation by 630-nm LED laser source powered at 1 W/cm2. CQDs have been tested in vitro and has been used as multicolor cellular imaging agent.

Conference Presentation

Citation Download Citation

Bryan Christian A. Karingal and Yih-Chih Hsu "Facile synthesis of fluorescent carbon quantum dots and their potential application in cancer theranostics", Proc. SPIE 11643, Biophotonics and Immune Responses XVI, 1164309 (5 March 2021); https://doi.org/10.1117/12.2584578

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available