In vivo elasticity mapping in human skin with AuT-based OCE

Mitchell A. Kirby; Peijun Tang; Hong-Cin Liou; John J. Pitre; Ruikang Wang; Matthew O'Donnell; Samuel Mandell; Russell Ettiger; Ivan Pelivanov

doi:10.1117/12.2577044

5 March 2021 In vivo elasticity mapping in human skin with AuT-based OCE

Mitchell A. Kirby, Peijun Tang, Hong-Cin Liou, John J. Pitre, Ruikang Wang, Matthew O'Donnell, Samuel Mandell, Russell Ettiger, Ivan Pelivanov

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Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 116450F (2021) https://doi.org/10.1117/12.2577044
Event: SPIE BiOS, 2021, Online Only

Abstract

Using numerical and analytical models of wave propagation in mechanically anisotropic materials, we highlight the complications associated with quantitative estimates of mechanical moduli in human skin. To obtain reliable, quantitative measurements of moduli in human skin, multiple aspects of mechanical wave propagation in structures typical of skin must be considered. Using a nearly incompressible transverse isotropic (NITI) model, preliminary measurements of both shear moduli (G and μ) in healthy in vivo human skin are presented.

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Mitchell A. Kirby, Peijun Tang, Hong-Cin Liou, John J. Pitre, Ruikang Wang, Matthew O'Donnell, Samuel Mandell, Russell Ettiger, and Ivan Pelivanov "In vivo elasticity mapping in human skin with AuT-based OCE", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450F (5 March 2021); https://doi.org/10.1117/12.2577044

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