Confocal air-coupled acoustic radiation force probe for the optical coherence elastography of tissues

Fernando Zvietcovich; Achuth Nair; Yogeshwari S. Ambekar; Manmohan Singh; Salavat R. Aglyamov; Michael D. Twa; Kirill V. Larin

doi:10.1117/12.2584510

5 March 2021 Confocal air-coupled acoustic radiation force probe for the optical coherence elastography of tissues

Fernando Zvietcovich, Achuth Nair, Yogeshwari S. Ambekar, Manmohan Singh, Salavat R. Aglyamov, Michael D. Twa, Kirill V. Larin

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Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 116450G (2021) https://doi.org/10.1117/12.2584510
Event: SPIE BiOS, 2021, Online Only

Abstract

We have designed and developed an air-coupled ultrasonic radiation force probe co-focused with a phase-sensitive optical coherence tomography system (ACUS-OCT). Our custom-made 1 MHz spherically focused piezo-electric transducer with a concentric circular opening of 10 mm diameter allows for the confocal micro-excitation of waves and the spatial (2D, 3D) motion measurement of tissues. Phantom studies demonstrated the capabilities of this probe to produce quasi-harmonic excitation up to 4 kHz for the generation of highly localized elastic waves. Experimental results in ocular tissues showed the highly localized 2D/3D elasticity mapping capabilities of this approach with great potential for clinical translation.

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Fernando Zvietcovich, Achuth Nair, Yogeshwari S. Ambekar, Manmohan Singh, Salavat R. Aglyamov, Michael D. Twa, and Kirill V. Larin "Confocal air-coupled acoustic radiation force probe for the optical coherence elastography of tissues", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450G (5 March 2021); https://doi.org/10.1117/12.2584510

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