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5 March 2021 Visualization of disrupted chromatin folding at nanoscale in early carcinogenesis via super-resolution microscopy
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Abstract
I will present our recent development of high-throughput super-resolution microscopy for robust imaging and reconstruction of super-resolution images on a widely used type of clinical samples – formalin-fixed, paraffin-embedded (FFPE) tissue, referred to as PathSTORM. Its application to visualize disrupted higher-order chromatin folding in early carcinogenesis will also be discussed.
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Yang Liu, Jianquan Xu, and Hongqiang Ma "Visualization of disrupted chromatin folding at nanoscale in early carcinogenesis via super-resolution microscopy", Proc. SPIE 11647, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX, 1164715 (5 March 2021); https://doi.org/10.1117/12.2579259
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