Presentation
1 August 2021 Experiencing the micro-world: a cell’s perspective
Amanda J. Wright, Tania Mendonca, Cathy Merry, Cameron Alexander, Katarzyna Lis-Slimak, Akosua Anane-Adjei, Lynn Paterson, Paul Dalgarno, Andrew Matheson, Manlio Tassieri
Author Affiliations +
Abstract
This talk will introduce a novel, recently developed, instrument that combines light sheet microscopy, optical trapping and multiplane imaging in a single platform capable of imaging 3D cultures of live cell over long time courses and mapping to these images the local mechanical properties of the material surrounding the cells. The presentation will highlight the wide-range of samples this instrument can study and discuss the analysis involved to evaluate the rheological properties of the material when either the trapping potential or the samples are non-isotropic.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Amanda J. Wright, Tania Mendonca, Cathy Merry, Cameron Alexander, Katarzyna Lis-Slimak, Akosua Anane-Adjei, Lynn Paterson, Paul Dalgarno, Andrew Matheson, and Manlio Tassieri "Experiencing the micro-world: a cell’s perspective", Proc. SPIE 11798, Optical Trapping and Optical Micromanipulation XVIII, 117980B (1 August 2021); https://doi.org/10.1117/12.2595901
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