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Chlamydiaceae family is consisted of intracellular bacteria pathogenic for both humans and animals. In this paper the nucleotide sequences of the gene encoding Pgp4 protein, the well-known virulence factor in Chlamydia, have been successfully transformed into the form of the GB-speckles. Strong discrimination was found between the relevant speckle patterns derived from three Chlamydiae spp., namely Chlamydia psittaci, Chlamydia abortus and Chlamydia trachomatis.
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Maria Khizhnyakova, Sergey Zaytsev, Yuriy Saltykov, Onega Ulianova, Sergey Ulyanov, Alexander Ulyanov, Valentina Feodorova, "The GB-speckles generated for the gene pgp4 as the promising model towards to differentiation of some Chlamydia spp.," Proc. SPIE 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine, 118450C (4 May 2021); https://doi.org/10.1117/12.2588535