Age-related changes in the brain functional connectivity during motor initiation

Nikita Frolov; Elena Pitsik

doi:10.1117/12.2591775

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4 May 2021 Age-related changes in the brain functional connectivity during motor initiation

Nikita Frolov, Elena Pitsik

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Proceedings Volume 11847, Saratov Fall Meeting 2020: Computations and Data Analysis: from Molecular Processes to Brain Functions; 118470V (2021) https://doi.org/10.1117/12.2591775
Event: Saratov Fall Meeting 2020, 2020, Saratov, Russian Federation

Abstract

Healthy aging affects structural and neurochemical properties of the human brain neural network. It also changes the brain functioning via the transformation of neural interactions both within and between functionally distinct brain areas. The age-related degradation of the brain functioning is evident on the behavioral level in terms of the decline in reaction time, low ability to execute and control complex motor actions, weak flexibility in learning new skills. In this paper we apply functional connectivity analysis to reveal the age-related changes in the integrative brain dynamic during the motor initiation before the dominant hand movements accompanied. Analyzing the whole-scalp electroencephalography (EEG) signals on the sensor level, we find higher theta-band coupling in the ipsilateral hemisphere.

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Nikita Frolov and Elena Pitsik "Age-related changes in the brain functional connectivity during motor initiation", Proc. SPIE 11847, Saratov Fall Meeting 2020: Computations and Data Analysis: from Molecular Processes to Brain Functions, 118470V (4 May 2021); https://doi.org/10.1117/12.2591775

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