Sparse frame acquisition toward fast volumetric dynamic optical coherence tomography imaging

Rion Morishita; Ibrahim Abd El-Sadek; Pradipta Mukherjee; Arata Miyazawa; Kiriko Tomita; Shuichi Makita; Yoshiaki Yasuno

doi:10.1117/12.2612715

7 March 2022 Sparse frame acquisition toward fast volumetric dynamic optical coherence tomography imaging

Rion Morishita, Ibrahim Abd El-Sadek, Pradipta Mukherjee, Arata Miyazawa, Kiriko Tomita, Shuichi Makita, Yoshiaki Yasuno

Author Affiliations +

Proceedings Volume 11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI; 119480I (2022) https://doi.org/10.1117/12.2612715
Event: SPIE BiOS, 2022, San Francisco, California, United States

Conference Poster

Abstract

In the biological and pharmaceutical research, there is a certain demand for label-free three-dimensional (3D) imaging of tissue function. Dynamic optical coherence tomography (OCT) has been demonstrated to fill this demand, but a very high-speed system is required for a volume acquisition of dynamic OCT. Here we demonstrate two new frame acquisition protocols which potentially enable the volumetric dynamic OCT by standard-speed OCT device with a reasonably short measurement time. One of the protocols takes multiple frames at a single location with a few hundred milliseconds interval. The other sequentially takes four frames at a single location, and then repeats this burst four-frame acquisition eight times with a few hundred milliseconds interval. These protocols were validated with in vitro and ex vivo samples. Both protocols gave reasonable dynamic OCT images.

Conference Presentation

Citation Download Citation

Rion Morishita, Ibrahim Abd El-Sadek, Pradipta Mukherjee, Arata Miyazawa, Kiriko Tomita, Shuichi Makita, and Yoshiaki Yasuno "Sparse frame acquisition toward fast volumetric dynamic optical coherence tomography imaging", Proc. SPIE 11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, 119480I (7 March 2022); https://doi.org/10.1117/12.2612715

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