Whole body imaging of mice in under 2 sec with single-sweep volumetric optoacoustic tomography (sSVOT)

Sandeep Kumar Kalva; Xosé Luís Deán-Ben; Michael Reiss; Daniel Razansky

doi:10.1117/12.2608652

3 March 2022 Whole body imaging of mice in under 2 sec with single-sweep volumetric optoacoustic tomography (sSVOT)

Sandeep Kumar Kalva, Xosé Luís Deán-Ben, Michael Reiss, Daniel Razansky

Proceedings Volume 11960, Photons Plus Ultrasound: Imaging and Sensing 2022; 1196005 (2022) https://doi.org/10.1117/12.2608652
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Accurate visualization of biological events at scales in the order of seconds requires high frame rate acquisition of image data from living tissues. Yet, fast imaging performance commonly comes at the cost of limited field-of-view (FOV) and reduced image quality. Here we present single-sweep volumetric optoacoustic tomography (sSVOT) for whole-body imaging of mice from head to tail within 1.8 s. sSVOT capitalizes on a custom-made spherical matrix array transducer together with a multi-beam illumination approach, the latter playing a critical role in maximizing the effective FOV. We compare the performance metrics to the previously reported whole-body mouse imaging implementations.

Conference Presentation

Citation Download Citation

Sandeep Kumar Kalva, Xosé Luís Deán-Ben, Michael Reiss, and Daniel Razansky "Whole body imaging of mice in under 2 sec with single-sweep volumetric optoacoustic tomography (sSVOT)", Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 1196005 (3 March 2022); https://doi.org/10.1117/12.2608652

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