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Lymphaticovenous anastomosis (LVA) is a surgical method of redirecting excess lymphatic fluid into the venous system to improve the lymphatic flow and prevent the recurrence of edema. In this work, using phantom and human volunteer experiments, we explore the potential of a portable LED-based dual-wavelength photoacoustic imaging system in 3D visualization of human lymphatic vessels and veins when using ICG as a contrast agent. Our results demonstrate that LED-based photoacoustic imaging system used in this study can visualize and separate lymphatic vessels and veins with high spatial resolution, and thus holds potential in guiding LVA procedure.
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Mithun Kuniyil Ajith Singh, Naoto Sato, Fumiyuki Ichihashi, Tetsuji Uemura, Yoshiyuki Sankai, "Guidance of lymphaticovenous anastomosis using LED-based photoacoustic lymphangiography: a human volunteer study," Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600R (3 March 2022); https://doi.org/10.1117/12.2610025