Fluorescence video endoscopic system for early cancer detection

A. Charles Lytle; J. Brian Dunn; Paul M. Paspa; Daniel R. Doiron; Oscar J. Balchum M.D.

doi:10.1117/12.17495

1 June 1990 Fluorescence video endoscopic system for early cancer detection

A. Charles Lytle, J. Brian Dunn, Paul M. Paspa, Daniel R. Doiron, Oscar J. Balchum M.D.

Proceedings Volume 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II; (1990) https://doi.org/10.1117/12.17495
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

A video system is being developed to allow the detection of cancerous lesions that are too small to be accurately identified visually or with x-ray. The system makes use of standard endoscopes and provides a video display of both the color image and a false color fluorescence image, with automated switching between the two views. Excitation of the fluorescence marker, Heinatoporphyrin Derivative (HpD) , or it ' 5 purified form , diheinatoporphyrin ether! ester (DHE) , is provided by a krypton ion laser operating in the violet. A brief discussion of fluorescence diagnostic theory and a description of the prototype system, its clinical use , and performance is reviewed.

Citation Download Citation

A. Charles Lytle, J. Brian Dunn, Paul M. Paspa, Daniel R. Doiron, and Oscar J. Balchum M.D. "Fluorescence video endoscopic system for early cancer detection", Proc. SPIE 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II, (1 June 1990); https://doi.org/10.1117/12.17495

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