Laser-assisted vascular anastomosis

Race L. Kao; George Tsao-Wu; George J. Magovern M.D.

doi:10.1117/12.17421

1 June 1990 Laser-assisted vascular anastomosis

Race L. Kao, George Tsao-Wu, George J. Magovern M.D.

Proceedings Volume 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II; (1990) https://doi.org/10.1117/12.17421
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

The milliwatt CO2 laser and a thermal activated binding compound (20% serum albumin) were used for microvascular anastomoses. Under general anesthesia, the femoral arteries (0.7 to 1.0 mm diameter) of 6 rats were isolated. After the left femoral artery in each rat was clamped and transected, the vessel was held together with 3 equidistant 10-0 Xomed sutures. The cut edges were coated 3 to 4 times with the albumin solution and sealed with the CO2 laser (power density = 120 W/cm2). The binding compound solidified to a translucent tensile substance which supported the anastomosis until self healing and repair were achieved. The right femoral artery was used as sham operated control. Complete hemostasis and patency were observed in every case immediately and at 1, 3, and 6 months following surgery. The binding compound absorbed most of the laser energy thus minimizing thermal injury to the underlying tissue. Mongrel dogs weighing 28 to 33 kg were anesthetized and prepared for sterile surgical procedures. In 5 dogs, the femoral and jugular veins were exposed, transected, and anastomosed using a CO2 laser (Sharplan 1040) with the binding compound. In another 12 dogs, cephalic veins were isolated and used for aortocoronary artery bypass procedures. The Sharplan 1040 CO2 laser and 20% albumin solution were utilized to complete the coronary anastomoses in 6 dogs, and 6 dogs were used as controls by suturing the vessels. Again, hemostasis, patency, and minimal tissue damage were observed immediately and 6 weeks after the procedures. Improved surgical results, reduced operating time, minimized tissue damage, and enhanced anastomotic integrity are the advantages of laser assisted vascular anastomosis with a thermal activated binding compound.

Citation Download Citation

Race L. Kao, George Tsao-Wu, and George J. Magovern M.D. "Laser-assisted vascular anastomosis", Proc. SPIE 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II, (1 June 1990); https://doi.org/10.1117/12.17421

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KEYWORDS

Arteries

Carbon dioxide lasers

Veins

Laser therapeutics

Laser tissue interaction

Tissues

Surgery

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