Photodynamic therapy of hypervascular cutaneous tissues in animal models using porphyrin or phthalocyanine activated by red light

J. Stuart Nelson M.D.; Arie Orenstein M.D.; Lih-Huei L. Liaw; Sol Kimel; Michael W. Berns

doi:10.1117/12.17453

1 June 1990 Photodynamic therapy of hypervascular cutaneous tissues in animal models using porphyrin or phthalocyanine activated by red light

J. Stuart Nelson M.D., Arie Orenstein M.D., Lih-Huei L. Liaw, Sol Kimel, Michael W. Berns

Author Affiliations +

Proceedings Volume 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II; (1990) https://doi.org/10.1117/12.17453
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

Continued iraprovement in the results of laser treatment of portwine stain (PWS) , with reduction in scarring, will depend on the ability to use lasers to induce selective injury of only the abnormal blood vessels in the dennis . Photodynamic therapy (PDT), using an exogenous photosensitizing drug specifically activated by a certain wavelength of light, may be used to destroy selectively certain targets in biological systems. The current study demonstrates, in the chicken comb animal model, that PDT using porphyrins and phthalocyanines activated by red light could be used to treat hypervascular derinal tissues.

Citation Download Citation

J. Stuart Nelson M.D., Arie Orenstein M.D., Lih-Huei L. Liaw, Sol Kimel, and Michael W. Berns "Photodynamic therapy of hypervascular cutaneous tissues in animal models using porphyrin or phthalocyanine activated by red light", Proc. SPIE 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II, (1 June 1990); https://doi.org/10.1117/12.17453

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available