1 June 1990 Preliminary results with dye-enhanced selective laser sclerosis of venous varicosities
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Abstract
Laser sclerosis (photosclerosis) of veins after injection of wavelength-specific dyes to enhance and localize energy absorption could provide a useful adjunct to current treatment options. To enhance the absorption of 808nm diode laser energy, ear veins of 18 rabbits were infused with 2-3cc of indocyanine green (maximum absorption 805nm) and exposed for 2 to 20 seconds. Animals were sacrificed between 0 and 28 days after operation. Discrete time intervals of laser exposure exist during which various sized vessels can be photosclerosed without significant thermal injury to the overlying tissue. The use of low power, diode lasers, in conjunction with wavelength-specific dyes, may provide a simple, effective, and cosmetically appealling alternative to current treatment options for superficial varicosities of the extremities.
© (1990) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven K. Libutti, Steven K. Libutti, Mehmet Cengiz Oz, Mehmet Cengiz Oz, Roy S. H. Chuck, Roy S. H. Chuck, Joseph S. Auteri, Joseph S. Auteri, Hanina Hibshoosh, Hanina Hibshoosh, Roman Nowygrod, Roman Nowygrod, Michael R. Treat, Michael R. Treat, "Preliminary results with dye-enhanced selective laser sclerosis of venous varicosities", Proc. SPIE 1200, Laser Surgery: Advanced Characterization, Therapeutics, and Systems II, (1 June 1990); doi: 10.1117/12.17455; https://doi.org/10.1117/12.17455
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