Application of CO laser for laser balloon angioplasty

Akira Miyamoto; Masami Sakurada; Kyoichi Mizuno; Akira Kurita; Haruo Nakamura; Akira Suda; Tsunenori Arai; Makoto Kikuchi

doi:10.1117/12.17523

1 July 1990 Application of CO laser for laser balloon angioplasty

Akira Miyamoto, Masami Sakurada, Kyoichi Mizuno, Akira Kurita, Haruo Nakamura, Akira Suda, Tsunenori Arai, Makoto Kikuchi

Author Affiliations +

Proceedings Volume 1201, Optical Fibers in Medicine V; (1990) https://doi.org/10.1117/12.17523
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

CO laser may be efficient for thermal fusion of intima of arterial wall without adventitial tissue damage because of high tissue absorption. To investigate the efficacy of CO laser as a laser bam for laser balloon angioplasty (LBA). CO laser was irradiated to aortic tissue through 3Oim polyethylene membrane and tissue temperature was measured by a thermistor. At 2Owatt/cm2 200joules/cm2 continuous laser exposure (CE), tissue temperature was above 100°C within a depth of 1mm and rapidly decreased to 60 °C or below between 2 and 3mm in depth. Moreover, adventitial temperature could be decreased by changing duty ratio (exposure duration/interval) of intermittent laser exposure (IE) despite of the same laser energy. Light microscopy showed high degree of medial coagulation necrosis in CE, however thermal coagulation was observed only at the surface of intima of aortic tissue in IE at duty ratio 1 / 2. These findings suggested CO laser could coagulate intimal layer with less deep thermal damage compared to Nd- YAG laser and that IE was better for superficial welding than CE at the same energy. We concluded that CO laser might be more efficient as a laser beam for LBA than Nd-YAG laser.

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Akira Miyamoto, Akira Miyamoto, Masami Sakurada, Masami Sakurada, Kyoichi Mizuno, Kyoichi Mizuno, Akira Kurita, Akira Kurita, Haruo Nakamura, Haruo Nakamura, Akira Suda, Akira Suda, Tsunenori Arai, Tsunenori Arai, Makoto Kikuchi, Makoto Kikuchi, } "Application of CO laser for laser balloon angioplasty", Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); doi: 10.1117/12.17523; https://doi.org/10.1117/12.17523

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