Ablation of atheroma by laser energy: a comparative study of the efficacy of different temporal rates of energy deposition

Donald J. Ramsay; Philip J. Walker; Nicola G. Dadswell; James May; James A. Piper; Christine Wacher

doi:10.1117/12.17621

1 June 1990 Ablation of atheroma by laser energy: a comparative study of the efficacy of different temporal rates of energy deposition

Donald J. Ramsay, Philip J. Walker, Nicola G. Dadswell, James May, James A. Piper, Christine Wacher

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Proceedings Volume 1202, Laser-Tissue Interaction; (1990) https://doi.org/10.1117/12.17621
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

Laser angioplasty continues to attract interest as a potential method for treating atherosclerotic arterial disease. Current efforts are aimed at finding the most effective combination of laser and delivery system. High energy pulsed ultraviolet or infrared lasers demonstrate good photoablative properties but there remain practical difficulties with the optical fibre delivery. Continuous wave lasers are widely used in conjunction with "hot-tip" fibres for thermal ablation but their direct (optical) ablation efficiency is low, causing significant surrounding thermal damage in soft tissue. While considerable attention has been directed previously at the ablative effects for different laser wavelengths, little systematic study has been made of the efficacy for different temporal rates of energy deposition. We have compared the efficacy for tissue ablation in cadaveric human aorta of three different laser systems with similar wavelengths in the visible (green) but different temporal rates of energy deposition. The laser sources were the continuous wave argon ion laser (514.5 nm), the high pulse energy, frequency doubled Nd:YAG laser (532 nm) and the copper vapour laser. The copper vapour laser is a high repetition rate, high average power, pulsed laser emitting in the green (511 nm) and yellow (578 nm) which has temporal characteristics intermediate between those of the Nd:YAG laser and the argon ion laser, and has the potential to be effective both for direct optical ablation and hot-tip thermal ablation.

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Donald J. Ramsay, Philip J. Walker, Nicola G. Dadswell, James May, James A. Piper, and Christine Wacher "Ablation of atheroma by laser energy: a comparative study of the efficacy of different temporal rates of energy deposition", Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); https://doi.org/10.1117/12.17621

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KEYWORDS

Laser ablation

Copper vapor lasers

Laser tissue interaction

Argon ion lasers

Injuries

Nd:YAG lasers

Pulsed laser operation

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