1 July 1990 Laser exposure effects on visual functions: measurement by electrophysiology: a selective review
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Since laser exposure in humans is usually limited to accident cases precise definition of its effects on visual function is difficult to come by. In order to determine more precisely these effects and at what exposure levels they occur animal models are required. This immediately poses the problem of how to appropriately ask the animal what it can see. Under the assumption that the visual system of lower primates is sufficiently similar to our own electrophysiological techniques allow us to trace the production of neuroelectric currents in the visual nervous system and thus to make conclusions of function based on signal analysis. These techniques (pattern and luminance electroretinograms and visual evoked potentials) are useful especially in delineating short-term effects (seconds). Since these signals are " large scale " responses their specificity can only be set by precisely delineating the stimuli used to evoke them a variant of the GIGO (garbage in garbage out) rule. The results while obtainable in no other way are therefore limited. Long term effects (chronic alterations in visual function) can also be demonstrated with these techniques. This paper will review both the techniques and the questions to which these techniques have been applied for laser exposure energies ranging from long-term low-level exposures to acute lesion-level exposures in the primate model. 2.
© (1990) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Elmar T. Schmeisser, Elmar T. Schmeisser, } "Laser exposure effects on visual functions: measurement by electrophysiology: a selective review", Proc. SPIE 1207, Laser Safety, Eyesafe Laser Systems, and Laser Eye Protection, (1 July 1990); doi: 10.1117/12.17827; https://doi.org/10.1117/12.17827

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