Detection of pathological changes in the architectonics of polycrystalline blood films using laser-induced polarization interferometry

D. Kvasniuk; L. Trifonyuk; A. Stashkevich; N. Kozan; V. Ushenko; O. Dunaiev; V. Kryvetskyi; I. Oliinyk; E. I. Kurek; V. I. Tkachuk

doi:10.1117/12.2616837

20 December 2021 Detection of pathological changes in the architectonics of polycrystalline blood films using laser-induced polarization interferometry

D. Kvasniuk, L. Trifonyuk, A. Stashkevich, N. Kozan, V. Ushenko, O. Dunaiev, V. Kryvetskyi, I. Oliinyk, E. I. Kurek, V. I. Tkachuk

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Proceedings Volume 12126, Fifteenth International Conference on Correlation Optics; 1212629 (2021) https://doi.org/10.1117/12.2616837
Event: Fifteenth International Conference on Correlation Optics, 2021, Chernivtsi, Ukraine

Abstract

The paper presents the results of the possibility of a polarization-interference approach to the analysis of microscopic images polycrystalline blood films of patients of benign and malignant prostate tumours with different degrees of differentiation. Measurements and analysis of maps and histograms of the distribution of the local contrast value of polarization-interference distributions of microscopic images of polycrystalline blood films of patients . Determination of the relationship between the statistical moments of the 1st - 4th orders characterizing the distributions of the local contrast value of the polarization-interference distributions of microscopic images of polycrystalline blood films of patients. Determination of statistical criteria for polarization-interference diagnosis of histological sections of biopsy of adenoma and adenocarcinoma with varying degrees of differentiation. Determination of sensitivity, specificity, accuracy of the polarization interferometry method for differential diagnosis of polycrystalline blood films of patients of adenoma and adenocarcinoma with varying degrees of differentiation.

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D. Kvasniuk, L. Trifonyuk, A. Stashkevich, N. Kozan, V. Ushenko, O. Dunaiev, V. Kryvetskyi, I. Oliinyk, E. I. Kurek, and V. I. Tkachuk "Detection of pathological changes in the architectonics of polycrystalline blood films using laser-induced polarization interferometry", Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 1212629 (20 December 2021); https://doi.org/10.1117/12.2616837

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KEYWORDS

Blood

Polarization

Prostate

Interferometry

Statistical analysis

Biopsy

Actinium

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