Optical modeling of compact Raman biomedical probe for endoscopic applications

Anastasia Shatskaya; Yulia Frolova; Dmitry Artemyev

doi:10.1117/12.2621286

27 May 2022 Optical modeling of compact Raman biomedical probe for endoscopic applications

Anastasia Shatskaya, Yulia Frolova, Dmitry Artemyev

Proceedings Volume 12144, Biomedical Spectroscopy, Microscopy, and Imaging II; 121440N (2022) https://doi.org/10.1117/12.2621286
Event: SPIE Photonics Europe, 2022, Strasbourg, France

Conference Poster

Abstract

Raman spectroscopy has become widespread in non-destructive, label-free cancer diagnosis during a clinical examination. The development of efficient and flexible devices is allowing for increasing the information content of the recorded Raman spectra and the final diagnostic accuracy in real-time with a high signal-to-noise ratio. In the present work, we developed the design of a miniature fiber optic probe for the implementation of the Raman spectroscopy method for potential endoscopic applications. The optical model of a fiber optic probe was designed using software Zemax OpticStudio. We studied 1) the filtering unit for suppression of laser radiation in the collection channel of the Raman probe made at the entrance to the spectrometer; 2) a set of optical fibers with microstructures at the end as elements that form a probing area of the test sample; 3) optical coupling of a bundle of optical fibers with the entrance slit of the spectrometer. As a result, the influence and prevention of the effect of laser radiation interference between coaxially located filters were shown, which leads to a decrease in the total optical filtering density of the laser wavelength and, accordingly, to a decrease in the signal-to-noise ratio of the system.

Citation Download Citation

Anastasia Shatskaya, Yulia Frolova, and Dmitry Artemyev "Optical modeling of compact Raman biomedical probe for endoscopic applications", Proc. SPIE 12144, Biomedical Spectroscopy, Microscopy, and Imaging II, 121440N (27 May 2022); https://doi.org/10.1117/12.2621286

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available