Super-resolution SERS spectral bioimaging

Zachary D. Schultz; Deben N. Shoup; Abigail E. Smith

doi:10.1117/12.2632824

3 October 2022 Super-resolution SERS spectral bioimaging

Zachary D. Schultz, Deben N. Shoup, Abigail E. Smith

Proceedings Volume 12203, Enhanced Spectroscopies and Nanoimaging 2022; 1220304 (2022) https://doi.org/10.1117/12.2632824
Event: SPIE Nanoscience + Engineering, 2022, San Diego, California, United States

Abstract

Advances in nanotechnology enable the detection of trace molecules from the enhanced Raman signal generated at the surface of plasmonic nanoparticles. We have developed technology to enable super-resolution imaging of plasmonic nanoparticles, where the fluctuations in the surface enhanced Raman scattering (SERS) signal can be analyzed with localization microscopy techniques to provide nanometer spatial resolution of the emitting molecule’s location. Additional work now enables the super-resolved SERS image and the corresponding spectrum to be acquired simultaneously. Here we will discuss how this approach can be applied to provide new insights into biological cells.

Conference Presentation

Citation Download Citation

Zachary D. Schultz, Deben N. Shoup, and Abigail E. Smith "Super-resolution SERS spectral bioimaging", Proc. SPIE 12203, Enhanced Spectroscopies and Nanoimaging 2022, 1220304 (3 October 2022); https://doi.org/10.1117/12.2632824

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available