1 July 1990 Tabletop CT system for 3-D in-vitro analysis of arterial flow and distensibility
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Abstract
We have developed a table-top CT system with high temporal and spatial resolution which can be used to quantify the 3-D flow patterns and arterial wall distensibility in intact arterial samples. Our system comprises of an x-ray image intensifier optically coupled to a linear photo-diode array camera. The arterial phantom or sample is irradiated by a narrow beam and a projection image of a thin slice through the sample is obtained with a temporal resolution of 17 ms. The spatial resolution in the CT images is 2 mm. The system can be used in two modes: flow quantification and dynamic motion quantification. In flow quantification mode an image is formed of a bolus of radio-opaque dye as it flows past the plane of interest. Repeated bolus injections, performed as the arterial phantom is rotated through 180, yield a series of timeposition projection images of the flowing bolus. These projection images are reconstructed using CT techniques to produce a 3-D time-position map of the flowing bolus. In dynamic motion quantification mode, time-position maps are obtained from many orientations as fluid is pumped through an arterial sample. Pulsatile flow is provided by a computer controlled pump which generates reproducible physiological flow and pressure waveforms. The collection of each projection image is gated to the beginning of the cardiac cycle. Again, usIng CT techniques we obtain cross-sectional images of the arterial sample at 60 points of the 'cardiac' cycle.
© (1990) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Maria Drangova, Maria Drangova, David W. Holdsworth, David W. Holdsworth, Aaron Fenster, Aaron Fenster, } "Tabletop CT system for 3-D in-vitro analysis of arterial flow and distensibility", Proc. SPIE 1231, Medical Imaging IV: Image Formation, (1 July 1990); doi: 10.1117/12.18835; https://doi.org/10.1117/12.18835
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