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1 July 1990 Role of color and spatial resolution in digital imaging colposcopy
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We have developed a practical digital imaging colposcope for use in research on early detection of cancerous and pre-cancerous tissue in the cervix. Several copies of the system have now been used in a variety of clinical and research environments. Two issues of considerable interest which emerged early in our work involved the roles of color and spatial resolution as they applied to digital imaging colposcopy. In each instance these qualities potentially have a significant impact on the diagnostic efficacy of the system. In order to evaluate the role of these parameters we devised and conducted a receiver operating characteristic (ROC) evaluation of the system. It is apparent from these tests that a spatial resolution of 512 x 480 pixel with 7 or 8 bits of contrast is adequate for the task. The more interesting result arises from the study of the use of color in these examinations; it appears that in general, contrary to the widely held perception of the physicians involved, color apparently provides the clinician with little or no diagnostic information. Indeed, in some instances, access to color seemed to confuse the physician and resulted in an elevated rate of false positives. Results of the ROC tests are presented in this paper along with their implications for further development of this imaging modality.
© (1990) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Eric R. Craine, John R. Engel, and Brian L. Craine M.D. "Role of color and spatial resolution in digital imaging colposcopy", Proc. SPIE 1232, Medical Imaging IV: Image Capture and Display, (1 July 1990);

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