Noninvasive optical biopsy of human oral lichen planus in vivo by optical coherence tomography

Yuliia Gruda; Jonas Golde; Jiawen Li; Marius Albrecht; Christian Schnabel; Dominik Haim; Guenter Lauer; Korinna Joehrens; Michaela Buckova; Robert A. McLaughlin; Julia Walther

doi:10.1117/12.2648925

17 March 2023 Noninvasive optical biopsy of human oral lichen planus in vivo by optical coherence tomography

Yuliia Gruda, Jonas Golde, Jiawen Li, Marius Albrecht, Christian Schnabel, Dominik Haim, Guenter Lauer, Korinna Joehrens, Michaela Buckova, Robert A. McLaughlin, Julia Walther

Author Affiliations +

Proceedings Volume 12354, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2023; 123540A (2023) https://doi.org/10.1117/12.2648925
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Modern noninvasive imaging techniques are used in many areas of medical research, particularly where an additional modality is required to support close monitoring during pre- or post-care. In oral medicine, the combination of an experienced clinician and supporting noninvasive optical devices for oral imaging, such as optical coherence tomography (OCT), may ensure improved diagnosis. In this study, the pathological features of lichenoid oral mucosa were noninvasively imaged with our miniaturized pen-like OCT probe and compared to adjacent healthy areas. The non-homogeneous epithelial (EP) layer, increased cornification of the EP surface and unidentifiable basement membrane are the most important features recorded.

Conference Presentation

Citation Download Citation

Yuliia Gruda, Jonas Golde, Jiawen Li, Marius Albrecht, Christian Schnabel, Dominik Haim, Guenter Lauer, Korinna Joehrens, Michaela Buckova, Robert A. McLaughlin, and Julia Walther "Noninvasive optical biopsy of human oral lichen planus in vivo by optical coherence tomography", Proc. SPIE 12354, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2023, 123540A (17 March 2023); https://doi.org/10.1117/12.2648925

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Optical coherence tomography

In vivo imaging

Biopsy

Medicine

Tissues

Medical diagnostics

Natural surfaces

Show All Keywords

Keywords/Phrases

Search In:

Publication Years