Development of an AI-assisted multi-spectral photoacoustic imaging for volumetric molecular tissue composition: a multi-frequency translational  approach

Valeria Grasso; Regine Willumeit-Roemer; Jithin Jose

doi:10.1117/12.2648059

9 March 2023 Development of an AI-assisted multi-spectral photoacoustic imaging for volumetric molecular tissue composition: a multi-frequency translational approach

Valeria Grasso, Regine Willumeit-Roemer, Jithin Jose

Author Affiliations +

Proceedings Volume 12379, Photons Plus Ultrasound: Imaging and Sensing 2023; 1237902 (2023) https://doi.org/10.1117/12.2648059
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The non-invasive assessment of biomarkers is crucial to predict chronic molecular changes and subsequent complications. Here, an AI-assisted volumetric multi-spectral photoacoustic imaging framework has been designed for enhanced visualization of tissue biomarkers and their monitoring. Besides, the multi-frequency spectral photoacoustic imaging approach has enabled multi-scale and multi-contrast imaging. The performances have been tested via tissue mimicking phantoms, at multiple-frequency bandwidths of 5−10 MHz, 10−22 MHz, and 15−29 MHz. Besides the impact of the frequency response of the ultrasound transducer on the PAI depth and resolution has been evaluated in detail, laying the fundamentals for the translation of PAI in clinics.

Conference Presentation

Citation Download Citation

Valeria Grasso, Regine Willumeit-Roemer, and Jithin Jose "Development of an AI-assisted multi-spectral photoacoustic imaging for volumetric molecular tissue composition: a multi-frequency translational approach", Proc. SPIE 12379, Photons Plus Ultrasound: Imaging and Sensing 2023, 1237902 (9 March 2023); https://doi.org/10.1117/12.2648059

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